Reza Mafi was born in Meshed (Khorasan), 1943.
First, he learned calligraphy in Edezadi school.
Mafi came to Tehran in 1958. From 1964, he went to calligraphy courses, in Hossein Mirkhani school. He was one of the first students that finished the four-year period of calligraphy courses in three years brilliantly.
He was greatly influenced by Mirza Qolam-Reza Isfahani's method. This master was one of the greatest calligraphers of 19th century. Reza Mafi continued to work in the same style, until the end of his life.
Reza Mafi came from a family of calligraphers and was himself a teacher of that art. In his paintings he experimented with the expressive qualities of nasta'liq, a hanging script developed in Iran during the fifteenth century which subsequently became the script of choice in almost all Persian poetic manuscripts. By focussing on the hanging tails of the letters, he reduced the script to its essentials to create a variety of expressive abstractions which as his style developed became increasingly minimalistic and elegant